Kuro5hin has an article called: Science and the Five-Star Hangover:

"Man, being reasonable, must get drunk," noted Lord Byron. It has been thus since some ancient human first left a pile of crushed grapes to fester for a while, took a swig, and eventually ended up with the caveman version of a lampshade on his head -- followed by the first hangover in human history. [...]

Sadly, the reports are somewhat grim: there is no surefire preventative for getting bombed, nor a cure for its second act, a killer hangover (other than not drinking, which is beside the point).

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